WebRESULTS Nintedanib in patients with chronic fibrosing interstitial lung diseases with progressive phenotype: the INBUILD® trial Kevin R. Flaherty,1 Athol U. Wells,2 Vincent Cottin,3 Anand Devaraj,4 Simon L.F. Walsh,5 Yoshikazu Inoue,6 Luca Richeldi,7 Martin Kolb,8 Kay Tetzlaff,9,10 Susanne Stowasser,9 Emmanuelle Clerisme-Beaty,9 Manuel … WebApr 11, 2024 · Wells AU, Flaherty KR, Brown KK, Inoue Y, Dev araj A, Richeldi L, et al.; ... Background In the INBUILD trial in patients with chronic fibrosing interstitial lung diseases (ILDs) and a progressive ...
EC_approval_nintedanib_ILD_PF Boehringer Ingelheim
WebKey findings. In the INBUILD trial, nintedanib slowed lung function decline by 57% across the overall study population, with an adjusted annual rate of decline over 52 weeks in FVC of -80.8 mL/year compared to -187.8 mL/year for placebo (difference, 107.0 mL/year [95% CI, 65.4 to 148.5]; p<0.001). The main secondary endpoints were the absolute ... WebOct 31, 2024 · A PF phenotype was defined based on the criteria used in the INBUILD trial. The median follow-up duration was 62.7 months. ... Flaherty KR, Wells AU, Cottin V, Devaraj A, Walsh SLF, Inoue Y, Richeldi L, Kolb M, Tetzlaff K, Stowasser S, et al. Nintedanib in progressive fibrosing interstitial lung diseases. N Engl J Med. … cinderella movie with cate blanchett
Dr. Elizabeth A. Belloli, MD Ann Arbor, MI - US News Health
WebKevin R. Flaherty: Conceptualization (supporting); visualization (supporting); writing – review and editing ... The INBUILD and INPULSIS trials were conducted in accordance with the principles of the Declaration of Helsinki and the Harmonized Tripartite Guideline for Good Clinical Practice from the International Conference on Harmonization ... WebMar 17, 2024 · Background: The primary analysis of the INBUILD trial showed that in subjects with progressive fibrosing interstitial lung diseases (ILDs), nintedanib slowed the … http://ildposters2024.com/PDF/ATS_INBUILD_Flaherty.pdf cinderella movie rodgers and hammerstein 1965