Cytoplasmic polyadenylation element
WebSequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation and early development. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR ( By similarity ). By … WebNov 24, 2015 · The cytoplasmic polyadenylation (CP) element, Pumilio binding element, and hexanucleotide polyadenylation signal are among the best understood motifs involved in CP, and translational regulation of …
Cytoplasmic polyadenylation element
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WebSep 12, 2024 · Cytoplasmic polyadenylation element-binding protein 4 (CPEB4) is known to associate with cytoplasmic polyadenylation elements (CPEs) located in the 3′ untranslated region (UTR) of specific mRNAs and assemble an activator complex promoting the translation of target mRNAs through cytoplasmic polyadenylation. Results WebJun 14, 2013 · The cytoplasmic polyadenylation element (CPE) recruits its binding protein CPEB1. 96 This binding can be stabilized, especially on noncanonical CPEs, by …
WebCPEB, or cytoplasmic polyadenylation element binding protein, is a highly conserved RNA-binding protein that promotes the elongation of the polyadenine tail of messenger … WebThe cytoplasmic polyadenylation element binding (CPEB) proteins are sequence-specific mRNA binding proteins that control translation in development, health, and disease. …
WebMay 23, 2014 · The poly(A) signal and nearby U-rich or GU-rich downstream sequence elements are recognized by two multi-protein complexes — namely, cleavage and … WebJun 12, 2013 · Introduction. The cytoplasmic polyadenylation element binding protein (CPEB) regulates the expression of proteins required for both early development and synaptic plasticity. 1 Previous studies on oogenesis and embryonic development have shown that translational regulation is required to establish polarity leading to cellular …
WebApr 23, 2004 · Cytoplasmic Polyadenylation Element (CPE)- and CPE-binding Protein (CPEB)-independent Mechanisms Regulate Early Class Maternal mRNA Translational …
WebNational Center for Biotechnology Information canal boats for sale in devonWebMar 30, 2024 · Further, as was the case with C12 RNA, Cl1 RNA contains a large masking element that prevents premature cytoplasmic polyadenylation during oocyte maturation. To examine the factors that may be involved in the cytoplasmic polyadenylation of both C12 and Cl1 RNAs, we performed UV cross-linking experiments in egg extracts. canal boats for sale glasson dockWebApr 4, 2024 · cytoplasmic polyadenylation element-binding protein 1, CPE-binding protein 1 GeneRIFs: Gene References Into Functions CPEB1 regulates the inflammatory immune response, phagocytosis, and alternative polyadenylation in microglia. MicroRNA-455-5p/CPEB1 pathway mediates Abeta-related learning and memory deficits in a … fisher paykel refrigerator reliabilityfisher paykel refrigerators in dallas txWebResults: We show that cytoplasmic polyadenylation element-binding protein 4 (CPEB4), which controls the translation of specific mRNAs by modulating their poly (A) tails, is highly expressed in visceral fat of obese but not lean humans and rodents (mice and rats), where it orchestrates an essential post-transcriptional reprogramming for … fisher paykel refrigerators ratedThe cytoplasmic polyadenylation element (CPE) is a sequence element found in the 3' untranslated region of messenger RNA. While several sequence elements are known to regulate cytoplasmic polyadenylation, CPE is the best characterized. The most common CPE sequence is UUUUAU, though there are other variations. Binding of CPE binding protein (CPEB) to this region promotes the extension of the existing polyadenine tail and, in general, activation of the mRNA for protein … fisher paykel refrigerator rf201adusx5 manualWebFunction. Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation and early … fisher paykel repair canberra