Rb1cc1-becn1-atg5
WebMar 21, 2024 · RB1CC1 (RB1 Inducible Coiled-Coil 1) is a Protein Coding gene. Diseases associated with RB1CC1 include Breast Cancer and Breast Adenocarcinoma . Among its … Web2 days ago · BECN1 is another common target of E2F1 and NFKB, but, unlike BNIP3, both E2F1 and NFKB induce the transcription of BECN1 [60, 61]. In addition, E2F1 induces the transcription of several other ATG ...
Rb1cc1-becn1-atg5
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Webwt becn1-ko - - ++ --15 - 17 - 42 - 1.0 1.1 4.6 1.3 1.2 2.0 lc3-ii/actb 63 - becn1 42 - actb mw (kda) lc3-i 15 - lc3-ii 17 - actb becn1 42 - 63 - lc3-i lc3-ii pik3c3 42 - actb 100 - 15 - 17 - p<0. ... WebDeficiency of atg5 reduces GFP-Lc3 ... class III phosphatidylinositol 3-kinase; PtdIns3P: phosphatidylinositol 3-phosphate; RB1CC1/FIP200: RB-1 inducible coiled coin 1; ROS: reactive oxygen species; RT-PCR: reverse transcriptase polymerase chain reaction; RUBCN/RUBICON: RUN and cysteine rich domain containing BECN1-interacting protein ...
WebBioGRID Interaction 948996 Between RB1CC1 And ATG5. Toggle navigation. Bio GRID 4.4 WebMar 22, 2024 · In prostate cancer suppression, abiraterone downregulates the expression levels of LC3, ATG5 and BECN1 to inhibit autophagy. It is worth mentioning that co-administration of 3-methyladenine as an autophagy inhibitor, enhances the potential of abiraterone in prostate cancer suppression via inducing a further decrease in LC3, ATG5 …
WebJun 30, 2024 · In cardiomyocytes, the immunoproteasome β5i subunit interacts with ATG5 to promote the ubiquitination and degradation of ATG5, thereby inhibiting autophagy and leading to cardiac hypertrophy . Moreover, saturated fatty acid palmitate induces ER stress and degrades ATG5 protein through the ER-associated protein degradation (ERAD) … WebNov 6, 2024 · (A-E) BECN1, atg5, atg7, RB1CC1, ATG16L1 knockout MEF or HeLa cells and WT cells were infected with SFTSV at an MOI of 1 for 24 h and 36 h. Cell lysates were …
WebBECN1 binds several further proteins that affect autophagosome formation. Partners that induce ... is regulated by two ubiquitination-like reactions. First, the ubiquitin-like molecule …
Webatg5 atg7 becn1 bmp2 braf ccl3 col10a1 cxcl1 fkbp8 gabarap gabarapl1 gabarapl2 gsk3b. igf1 il1b il24 il3 il6r il6st inhba ins irf1 kmt2a lamp1 lamp2 map1lc3a map1lc3c mir29b2 … cu ft to gallonWebMay 16, 2024 · BECN1 deficiency results in embryonic lethality, whereas BECN1 +/− mice displayed a loss of RPE and photoreceptors integrity during photo-oxidative stress. … cu ft to dekathermWebCancers 2024, 11, 1209 2 of 18 colorectal cancer in the in vitro and in vivo models [12,13]. For these reasons, targeting the autophagy process is a promising alternative in the … eastern information center uc riversideWebNov 6, 2024 · (A-E) BECN1, atg5, atg7, RB1CC1, ATG16L1 knockout MEF or HeLa cells and WT cells were infected with SFTSV at an MOI of 1 for 24 h and 36 h. Cell lysates were … cu ft to acftWebThe Atg12–Atg5 conjugate then interacts noncovalently with Atg16 to form a large complex. The second complex, LC3/Atg8, is cleaved at its C-terminus by Atg4 protease to generate the cytosolic LC3-I. LC3-I is conjugated to phosphatidylethanolamine (PE) in a ubiquitin-like reaction that requires Atg7 and Atg3 (E1 and E2-like enzymes, respectively). cu ft to galsWebJun 2, 2024 · Generally, HeLa, MEF, HEK-293T, THP-1, and BMDM are widely used cell lines, while STING1 −/− mice or xenograft models are widely used animal models to study the function of STING1 in autophagy ... eastern inn cape codWebJun 8, 2024 · Becn1 F121A knockin mutation reverses decreased autophagy in neurospheres from older mice. (A) Lysates from DMSO and Baf A 1 treated neurosphere … cu ft to ccf